Institute regarding Medicine (US) Panel to the Understanding the Biology away from Sex and you can Gender Distinctions; Wizemann TM, Pardue ML, writers. Exploring the Biological Benefits to help you Peoples Fitness: Does Sex Number? Washington (DC): Federal Academies Press (US); 2001.
- Material
- Hardcopy Type during the National Academies Drive
Abstract
The fresh physical differences between the fresh sexes have long been acknowledged from the the latest biochemical and you may cellular accounts. Fast advances in molecular biology has found the new hereditary and unit bases out of a lot of sex-established variations in health and person problem, some of which was attributed to sexual genotype-XX regarding the female and you will XY on male. Genes toward sex chromosomes will be expressed in a different way anywhere between males and you can people from the exposure of often unmarried otherwise twice copies of your own gene and since of one’s phenomena of different meiotic effects, X inactivation, and you will hereditary imprinting. The brand new inheritance out-of often a masculine or a lady genotype is after that influenced by the main cause (maternal or paternal) of the X-chromosome. The fresh cousin roles of your sex chromosome genetics and their phrase explains X-chromosome-connected condition which is planning illuminate the reason why to have heterogeneous expression of a few ailment within this and you will between the sexes.